This excerpt is from the Huberman Lab episode titled "Dr. Layne Norton: Tools for Nutrition & Fitness." It covers what the peer-reviewed research says about exercise, nutrition, supplementation, and health. Here we are discussing if resistance training needs to be done "to failure" — the inability to further move the resistance in good form for that set. It turns out the answer is relevant if you are seeking hypertrophy and/or strength.
Keep in mind that resistance training has been recommended by numerous guests on the podcast for both women and men regardless of whether you’re seeking hypertrophy, or simply strength increases. In fact, resistance training is turning out to be one of the best ways to improve your immediate and long-term health and longevity per se.