In this episode of The Human Upgrade podcast, Dave Asprey sits down with Siggi Clavien, founder and CEO of Equilibrium Labs, for an in-depth discussion on liver health and how it impacts longevity, brain function, and overall well-being. They explore how the liver’s ability to detoxify, regenerate, and support metabolic processes is critical to achieving optimal performance and preventing chronic diseases.
Siggi shares insights on nonalcoholic fatty liver disease (NAFLD), the effects of processed foods, fructose, seed oils, and pharmaceuticals on liver function, and how liver health ties into metabolic syndrome, cardiovascular disease, and cognitive function. Together, they discuss the importance of regular liver scans, holistic liver care, and the role of supplements like Equilibrium Labs’ Deliverance in reversing liver damage and optimizing liver function.
Listeners will discover practical wellness tips on how to support their liver through nutrition, natural remedies, hydration, and mindfulness practices. They also cover how substances like glutathione, antioxidants, and coffee can enhance liver function and protect against environmental toxins.
Whether you’re interested in holistic health, vitality, fitness, or natural detox strategies, this episode is packed with actionable advice for maintaining a healthy lifestyle and aging gracefully. Learn how taking care of your liver can lead to better brain clarity, energy levels, and resilience against modern health threats.
Resources:
2025 Biohacking Conference – https://biohackingconference.com/2025
De-liver-ance – https://us.loveyourliver.com/discount/DAVE (Use code DAVE at checkout for a discount!)
The Liver Clinic – https://theliverclinic.com
Equilibrium Labs – https://equilibriumlabs.com
Danger Coffee – https://dangercoffee.com
Dave Asprey’s Website – https://daveasprey.com
Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books
Dave Asprey’s Linktree – https://linktr.ee/daveasprey
Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com
Own an Upgrade Labs – https://ownanupgradelabs.com
Upgrade Labs – https://upgradelabs.com
40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement – https://40yearsofzen.com
Timestamps:
• 00:00 Intro
• 00:00 Introduction and Liver Basics
• 01:46 Guest Introduction and Liver Health Insights
• 02:16 Understanding Liver Scans and Lab Panels
• 05:13 Fatty Liver Disease: Causes and Consequences
• 07:07 Diet and Liver Health
• 09:47 Supplements and Liver Function
• 11:53 Advanced Liver Health Strategies
• 14:05 Biohacking and Liver Health
• 17:41 Deliverance Supplement and Its Benefits
• 23:12 Liver Health and Longevity
• 31:12 Biohacking: The Path to Consciousness and Longevity
• 32:29 The Liver: The Body’s Regenerative Powerhouse
• 34:48 Gut Microbiome and Liver Health Connection
• 35:59 Lipopolysaccharides: The Hidden Toxins
• 40:44 Coffee: A Surprising Ally for Liver Health
• 43:16 Mold Toxins: The Silent Liver Destroyers
• 48:43 Hormone Health and the Liver
• 52:19 Type 2 Diabetes, Menopause, and Liver Health
• 52:43 The Impact of Lifestyle on Liver Health
• 54:57 The Importance of Bile and Gallbladder Health
• 58:06 Genetics, Toxins, and Liver Resilience
• 01:06:25 Conclusion: Investing in Liver Health for a Better Life
Connect with Dave Asprey!
Website: https://daveasprey.com
TikTok: https://www.tiktok.com/@daveaspreyofficial
Instagram: https://www.instagram.com/dave.asprey/
Facebook: https://www.facebook.com/Daveaspreyofficial/
Twitter: https://twitter.com/daveasprey
YouTube: https://www.youtube.com/c/daveaspreybpr
The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ and https://m.facebook.com/Thehumanupgrade/
