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    Home » Control Your Vagus Nerve to Improve Mood, Alertness & Neuroplasticity

    Control Your Vagus Nerve to Improve Mood, Alertness & Neuroplasticity

    Mal AntoniBy Mal AntoniJune 23, 2025 All Videos 2 Mins Read
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    In this episode I explain how your vagus nerve—an extensive neural pathway linking your brain and body in both directions—powerfully regulates your mood, digestion, alertness and even certain food cravings, and I explain how you can activate certain vagus nerve pathways to improve your heart rate variability (HRV), a key marker of health and longevity. I also explain how to control vagal pathways to enhance your focus and alertness to improve learning and neuroplasticity. And I explain how your vagus nerve controls levels of serotonin in both your gut and brain, impacting your mood and emotional resilience and how to keep that pathway robust.

    Episode show notes: https://go.hubermanlab.com/K36mJhe

    *Thank you to our sponsors*
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    *Timestamps*
    00:00:00 Vagus Nerve
    00:02:43 Sponsors: LMNT & Joovv
    00:05:41 Cranial Nerves, Inputs (Afferents) & Outputs (Efferents), Sensory & Motor
    00:12:40 Vagus Nerve & Sensory Pathways, Body & Brain
    00:18:30 Sensory Information, Chemical & Mechanical Information
    00:23:49 Sympathetic & Parasympathetic Nervous Systems, Vagus Nerve, Tool: Calming & Auricular (Ear) Sensation
    00:30:19 Sponsors: AG1 & ROKA
    00:33:38 Vagus Nerve Motor Outputs
    00:36:00 Autoregulation, Improving Heart Rate Variability (HRV) Tools: HR Deceleration
    00:49:46 Aging, Declining HRV, Health, Activity, Tool
    00:52:31 Tool: Exercise, Increase Alertness for Cognitive & Physical Activity, Motivation
    01:04:26 Sponsor: Function
    01:06:14 Adult Neuroplasticity & Learning, Acetylcholine, Alpha GPC Nicotine
    01:11:48 Tools: High-Intensity Exercise, Increase Alertness, Focus & Learning; Sleep
    01:18:14 Serotonin, Gut, Brain & Mood, Depression & SSRIs
    01:21:34 Serotonin, Improve Mood & Gut Health, Irritable Bowel Syndrome (IBS), Tools: Low-Sugar Fermented Foods, Tryptophan
    01:28:49 Mood, Depression, Gut Health & Vagal Signaling, Probiotics
    01:32:12 Calming Down via Vagus Nerve, Tool: Neck Peri-Arterial Vagus Stretch
    01:42:00 Tools: Calming Down, Humming, Extended Exhales
    01:46:38 Recap
    01:48:46 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter

    Disclaimer & Disclosures: https://www.hubermanlab.com/disclaimer

    Mal Antoni

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