Ready to learn about the secret compounds, molecules, nootropics, and stacks that Big Pharma doesn’t want you to know about? This episode is packed with the exact dopamine-boosting compounds, stacks, and biohacking protocols that top performers are using to supercharge human performance, brain optimization, and long-term resilience.
Host Dave Asprey sits down with Lucas Aoun, Australia’s leading biohacker and founder of Ergogenic Health. Known for his fearless, data-driven experimentation, Lucas specializes in nootropics, dopamine modulation, mitochondria, and functional medicine. He’s spent over a decade testing underground nootropics, hormone-based strategies, and metabolic stacks to achieve elite-level brain and body performance.
Together, they explore Russian-developed compounds like Bromantane and ITPP, revealing how these rare substances impact dopamine regulation, neuroplasticity, and mental drive. You’ll learn how to upregulate tyrosine hydroxylase (your brain’s dopamine switch), build a personalized dopamine stack to boost confidence and focus, and avoid the misleading supplements that quietly kill your ambition.
They also break down the relationship between dopamine and testosterone, and why optimizing both is essential for masculine identity, libido, and high-agency living. The episode dives into DHT science, prolactin suppression, GABA balance, and how to design your own dopamine protocol using proven brain optimization techniques and biohacking supplements.
Other key topics include why ashwagandha may harm motivation, how cold therapy can influence neurotransmitters, and how to enhance sleep with strategic nootropics and amino acids. You’ll also hear about fasting, ketosis, sleep optimization, cabergoline, ciproheptadine, and why your metabolism and mitochondrial health are core to sustainable motivation.
You’ll Learn:
• The #1 Russian compound for explosive dopamine and drive
• Why most “calming” supplements destroy your ambition
• How dopamine and DHT shape masculinity and performance
• Advanced biohacks for sleep, motivation, libido, and mood
• The truth about serotonin dominance and how to escape it
• Which functional medicine tools enhance brain energy and metabolism
• How to build your own dopamine protocol using proven nootropics
• Why mitochondrial health is the hidden key to motivation and mood
This is essential listening for anyone serious about biohacking, brain optimization, hormone hacking, functional medicine, emotional resilience, and building a state of unstoppable energy. Whether you’re into ketosis, carnivore, or simply looking for the most effective dopamine boosters to feel like your most powerful self, this episode delivers.
Extended Keywords:
dopamine boosters, russian nootropics, bromantane benefits, biohacking dopamine, boost motivation naturally, dopamine stack, lucas aoun podcast, dave asprey dopamine, nootropics for energy, secret russian compounds, brain optimization, biohacking supplements, increase dopamine levels, functional medicine hacks, hormone optimization, dopamine and testosterone, neuroplasticity hacks, superhuman energy, underground nootropics, dopamine protocols
Resources:
• Lucas’s Website: https://www.boostyourbiology.com/
• Lucas’s YouTube: https://www.youtube.com/c/boostyourbiology
Timestamps:
0:00 – Trailer
0:49 – Intro
1:35 – Dopamine Hacking & Bromantane
4:25 – Modafinil, Adamantane, and More
9:11 – Risks and Balancing Neurotransmitters
11:11 – Masculinity, DHT, and Hormones
14:12 – Natural Aphrodisiacs and Dopamine Stacks
17:26 – Ashwagandha, Cortisol, and Stress
21:09 – Supplements for Sleep and Neurochemistry
39:10 – Oxalates, Collagen, and Mitochondrial Health
47:39 – Biohacking for Women & Hormone Balance
51:26 – Supplements to Avoid
54:45 – Mitochondrial Supplements & Endurance
1:02:43 – Closing & Where to Find Lucas
Connect with Dave Asprey!
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Dave Asprey’s BEYOND Conference: https://beyondconference.com/
Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated/
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40 Years of Zen: https://40yearsofzen.com
