In this episode, Luke Storey sits down with Dr. Chris Rhodes, who is a scientist and co-founder of Mimeo, to explore the biology of fasting and the future of biomimetic medicine.
They discuss how humans are wired for feast-and-famine cycles, why constant eating keeps the body locked in processing mode, and how fasting triggers cellular repair, autophagy, and hormone balance. Dr. Rhodes breaks down the unique effects of intermittent fasting, 24-hour resets, alternate-day fasting, and longer supervised fasts showing what really happens at different stages.
The conversation also covers Mimio, a fasting-mimicking supplement built from molecules the body naturally produces during extended fasts. Backed by clinical studies, it has shown benefits for metabolism, appetite, cognition, and even biological age.
If you’ve ever wondered why fasting matters, how to approach it safely, or whether there are ways to make it easier, this episode explains it in a clear and practical way.
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Resources:
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