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    Home » The Science of Gratitude & How to Build a Gratitude Practice | Huberman Lab Essentials

    The Science of Gratitude & How to Build a Gratitude Practice | Huberman Lab Essentials

    Mal AntoniBy Mal AntoniOctober 23, 2025 All Videos 2 Mins Read
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    In this Huberman Lab Essentials episode, I explore the science of gratitude and how to develop an effective, research-supported gratitude practice.

    I explain why common gratitude practices (like simply listing things you’re grateful for) are far less impactful than engaging in story-based gratitude practices. I also explain how being grateful activates specific brain regions, which enhance calm, social connection and motivation, while reducing anxiety and inflammation. Finally, I share why we can’t simply trick our brains into feeling grateful and describe a practical weekly gratitude practice that will improve both your mental and physical well-being.

    Episode show notes: https://go.hubermanlab.com/bpHpAWB

    Huberman Lab Essentials are short episodes focused on essential science and protocol takeaways from past full-length Huberman Lab episodes. Watch the full-length episode:

    Watch more Huberman Lab Essentials episodes: https://youtube.com/playlist?list=PLPNW_gerXa4OGNy1yE-W9IX-tPu-tJa7S

    *Follow Huberman Lab*
    Instagram: https://www.instagram.com/hubermanlab
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    LinkedIn: https://www.linkedin.com/in/andrew-huberman
    Website: https://www.hubermanlab.com
    Newsletter: https://www.hubermanlab.com/newsletter

    *Timestamps*
    00:00:00 Gratitude
    00:00:30 Gratitude Practice Benefits
    00:03:22 Pro-Social vs Defensive Behaviors, Gratitude
    00:06:25 Serotonin, Brain & Context; Gratitude Mindset
    00:12:21 Context, Can You Lie to Yourself?
    00:13:06 Effective Gratitude Practice, Tools: Receiving Gratitude, Story
    00:19:36 Tool: Find & Revisit Inspirational Stories
    00:24:19 Heartfelt Intention, Genuine Thanks
    00:26:31 Gratitude Practice Benefits for Anxiety, Fear & Motivation
    00:28:58 Gratitude Practice Benefits for Immune System
    00:31:31 Recap: Establishing an Effective Gratitude Practice

    Disclaimer & Disclosures: https://www.hubermanlab.com/disclaimer

    Mal Antoni

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