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    Home » Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

    Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

    Mal AntoniBy Mal AntoniDecember 25, 2025 All Videos 2 Mins Read
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    In this Huberman Lab Essentials episode, my guest is Dr. Kyle Gillett, MD, a dual board-certified physician in family medicine and obesity medicine and an expert in optimizing hormone levels to improve overall health.

    We explain how to improve hormone levels across the lifespan in both men and women using behavioral, nutritional and exercise-based tools. We also discuss common clinical topics, including hormone testing, PCOS, hair loss, testosterone replacement therapy (TRT) and peptides, focusing on potential benefits, tradeoffs and risks.

    Episode show notes: https://go.hubermanlab.com/EkpDEyt

    Watch more Huberman Lab Essentials: https://youtube.com/playlist?list=PLPNW_gerXa4OGNy1yE-W9IX-tPu-tJa7S&si=a1_sA7rUT-fE0OM5

    *Timestamps*
    00:00:00 Kyle Gillett
    00:00:36 Hormone Health; Women vs Men, Tool: Hormone Testing
    00:02:35 Tool: Big 6 Lifestyle Pillars to Optimize Hormone Health
    00:04:32 Diet, Individualization; Bloodwork & Frequency
    00:05:35 Exercise, Zone 2 Cardio; Caloric Restriction
    00:06:51 Intermittent Fasting, Growth Hormone, IGF-1
    00:09:20 Hormones & Sleep, Growth Hormone, Menopause, Andropause, TRT
    00:11:43 Testosterone & Women, SHGB
    00:13:34 Dihydrotestosterone (DHT), Androgens; Turmeric & Black Pepper; Hair Loss
    00:16:47 Polycystic Ovarian Syndrome (PCOS), Symptoms, Metformin, Inositol
    00:20:13 Cannabis, Alcohol, Testosterone
    00:21:47 Males & Testosterone, TRT, Prostate Cancer
    00:23:04 Prolactin, Dopamine “Wave Pool”, Tool: Casein & Gluten
    00:24:23 Social Relationships & Hormones, Tool: Planning for Crisis
    00:26:22 Peptides, Growth Hormone & Risk; BPC 157, Sourcing & LPS
    00:32:02 Melanotan, Uses & Risks
    00:34:05 Spiritual Health, Interdisciplinary Health Integration
    00:36:43 Caffeine & Hormones, Sleep; Acknowledgements

    #HubermanLab

    Disclaimer & Disclosures: https://www.hubermanlab.com/disclaimer

    Mal Antoni

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