Dr. Keith Humphreys is a professor of psychiatry and behavioral sciences at Stanford School of Medicine and a leading expert on treating addictions, drug laws and policy. We discuss all the major addictive substances and behaviors, including alcohol, opioids, gambling, stimulants, nicotine, cannabis and more, focusing on how genetics and certain use patterns shape addiction susceptibility. We discuss the best evidence-based tools for recovery, from 12-step programs to emerging treatments such as psychedelics and ibogaine. Anyone interested in making better choices for their health and/or seeking to avoid or overcome addictions ought to benefit from this episode.
Episode show notes: https://go.hubermanlab.com/Ir6zQnv
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*Dr. Keith Humphreys*
Stanford academic profile: https://profiles.stanford.edu/keith-humphreys
Book: https://amzlink.to/az0Q03kPwfVJb
Stanford-Lancet Commission on the North American Opioid Crisis: https://opioids.stanford.edu
Stanford Network on Addiction Policy: https://addictionpolicy.stanford.edu
The Washington Post: https://www.washingtonpost.com/people/keith-humphreys
The Atlantic: https://www.theatlantic.com/author/keith-humphreys
Publications: https://profiles.stanford.edu/keith-humphreys?tab=publications
X: https://x.com/KeithNHumphreys
*Timestamps*
00:00:00 Keith Humphreys
00:03:22 Addiction; Genetic Risk
00:09:14 Alcohol Use Disorder & Alcoholism; Genetic Predisposition & Addiction Risk
00:18:03 Sponsors: David & BetterHelp
00:20:37 Women & Alcohol Use; Young Adults; Cannabis Use
00:23:36 Health Benefit to Alcohol?, Red Wine, Cancer Risk; Social Pressure
00:31:47 Alcohol in Social Gatherings, Social Anxiety, Vulnerability, Work & Dates
00:37:41 Old vs New Cannabis & THC Levels; Smoked vs Edible Forms
00:44:38 Cannabis & Psychosis Risk; Cardiac Health; Youth Cannabis Use & Transition to Adulthood
00:52:29 Sponsor: AG1
00:54:13 Industries of Addiction, Regulation; Gambling, Slot Machines, Novelty; Casinos
01:05:28 Decriminalization vs Legalization; Cannabis, Gateway Drug?
01:08:50 Psylocibin or LSD, Addiction Treatment; Microdosing, Clinical Trial Challenges
01:18:58 Sponsor: Helix Sleep
01:20:32 Brain Plasticity & Age; Ketamine, Depression, Transcranial Magnetic Stimulation (TMS)
01:28:10 SSRIs, Mass Shootings, Suicide, Side Effects; Drug Approval; Ibogaine & PTSD
01:36:10 Caffeine Addiction?; Stimulants & Rehab; Prescription Stimulants & ADHD
01:44:04 Nicotine, Mistaking Withdrawal for Benefit
01:47:24 Sponsor: LMNT
01:48:44 Tool: How to Talk to Someone with Addiction
01:55:23 Perception of Addicts, Character Defect, Pain
02:00:58 Overcoming Addiction, Immediate Rewards, AA; Addict & Co-Dependency?
02:09:53 Longterm Drug Use, Dopamine, Cues & Relapse; Social Media
02:16:21 Brain Stimulation, TMS; Homelessness, Substance Use & Rehab
02:26:11 Addiction Treatment Policy, Rehab & Insurance
02:29:08 Tool: 12-Step Programs, AA, Accessibility & Benefits
02:38:08 AA, Higher Power, Cult?; Flexibility, Tool: Open AA Meetings
02:44:38 GLP-1s, Weight Loss, Alcohol Addiction; Pharmaceutical Advertisements
02:52:39 Social Media Addiction, Tool: Avoiding Social Media Strategies
02:58:36 “Failure to Launch”, Youth, Video Games, Social Media; Recovery Pathways
03:04:13 AA as an Action Program, Tool: Try Different AA Meetings
03:08:21 Hospice, Death, Overcoming Fear of Death
03:13:54 Addiction to Escape Death?, Desire for Oblivion
03:18:11 Men vs Women & Addiction; Lying; Relapse; Fentanyl & Addiction Advice
03:24:27 Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter
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