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    Home » Essentials: Science of Stress, Testosterone, Aggression & Motivation | Dr. Robert Sapolsky

    Essentials: Science of Stress, Testosterone, Aggression & Motivation | Dr. Robert Sapolsky

    Mal AntoniBy Mal AntoniJuly 10, 2025 All Videos 2 Mins Read
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    In this Huberman Lab Essentials episode my guest is Dr. Robert Sapolsky, PhD, a professor of biology, neurology and neurological sciences at Stanford University.

    We discuss different types of stress and how our perception of stress as harmful or beneficial largely depends on context. He also explains how testosterone amplifies pre-existing behaviors and tendencies, and he highlights the crucial role of estrogen in supporting brain and body health. We also discuss daily cognitive practices for stress mitigation and how modern life, influenced by social media and complex social hierarchies, shapes our responses to stress.

    Episode show notes: https://go.hubermanlab.com/MPalfmV

    Huberman Lab Essentials are short episodes focused on essential science and protocol takeaways from past full-length Huberman Lab episodes. Watch the full-length episode: https://youtu.be/DtmwtjOoSYU

    Watch more Huberman Lab Essentials episodes: https://youtube.com/playlist?list=PLPNW_gerXa4OGNy1yE-W9IX-tPu-tJa7S

    *Follow Huberman Lab*
    Instagram: https://www.instagram.com/hubermanlab
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    LinkedIn: https://www.linkedin.com/in/andrew-huberman
    Website: https://www.hubermanlab.com
    Newsletter: https://www.hubermanlab.com/newsletter

    *Timestamps*
    00:00:00 Robert Sapolsky
    00:00:23 Positive & Negative Stress; Excitement, Amygdala
    00:02:47 Testosterone & Brain, Aggression, Hierarchy
    00:06:27 Testosterone, Motivation, Challenge & Confidence
    00:11:01 Dopamine, Testosterone & Motivation
    00:13:28 Estrogen, Brain & Health, Replacement Therapies
    00:15:21 Stress Mitigation
    00:19:17 Cognitive Practices for Stress Mitigation, Individual Variability, Consistency
    00:21:36 Stress, Perception & Individual Differences
    00:23:58 Context, Stress & Brain
    00:27:05 Social Media, Context, Multiple Hierarchies
    00:30:15 Acknowledgments

    Disclaimer & Disclosures: https://www.hubermanlab.com/disclaimer

    Mal Antoni

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