Focusing only on supplements without supporting your body’s own GABA production can backfire over time. Dr. Gundry discusses why it’s essential to maintain healthy GABA levels, the role of glutamate conversion, and how natural compounds like kava, CBD, CBG, and other cannabinoids can help protect against GABA depletion by binding to GABA receptors.
Is a GABA deficiency the root cause of your anxiety? In this eye-opening episode, Dr. Gundry and his guest, Dr. Scott Sherr dive deep into the world of GABA, a crucial neurotransmitter that acts as the brain’s "brakes". We’ve all heard about dopamine and serotonin, but it’s the balance between glutamate and GABA that’s responsible for 80% of your brain’s neurotransmission. Learn why modern life, with its "hustle culture" and constant stimulation, is causing a widespread GABA deficiency. This deficiency can manifest as anxiety, stress, insomnia, and even depression.
Discover how a low GABA system leads to an overstimulated brain and why simply taking a GABA supplement might not be the answer. We’ll discuss why the supplement is often too large to cross the blood-brain barrier , and what a positive reaction to it could mean for your health. Instead, learn about the right ways to support your GABA system through diet, lifestyle, and a targeted "obligate pair strategy" of supplementation.
00:00 – The Role of GABA: The brain’s "brakes" and the glutamate balance.
02:18 – Modern Life and GABA Deficiency: The impact of hustle culture and cortisol.
05:01 – The Dopamine Connection: How dopamine hits deplete your GABA.
07:00 – How to Test for GABA Deficiency: Why direct testing doesn’t work and what to check instead.
11:00 – Debunking the Serotonin Myth: Why depression isn’t a serotonin deficiency.
15:00 – GABA vs. Gabapentin & Alcohol: The difference between natural and synthetic GABA enhancers.
18:00 – The Leaky Brain: Why taking a GABA pill might not work.
19:00 – Mocktails & GABA: Are kava and other herbs effective?.
22:00 – The Mushroom Connection: A powerful compound that supports GABA.
26:00 – Answering a Listener’s Question: What to look for in a GABA supplement.
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