Longevity isn’t about just living longer, but rather living better and longer.
Today, I sit down with Dr. Greg Bailey, a former emergency room physician turned biotech investor who now operates at the forefront of longevity science. After a decade in emergency medicine, he transitioned into drug development and cutting-edge research focused on extending healthspan, not just lifespan. We get into the mechanics of ketosis and why metabolic flexibility may matter more than extreme dieting, and the growing role of AI in medicine. Beyond the tech, we address supplement credibility, flawed research, and why connection, purpose, and education remain foundational to real longevity.
If you’re serious about biohacking, metabolic health, and the future of regenerative medicine, this conversation sets the tone.
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You’ll Learn:
[00:00] Introduction
[01:29] The creativity and absurdity Greg witnessed in emergency room patients
[03:14] Different motivations for pursuing longevity and how desired lifespan changes based on projected health
[07:46] Cutting-edge longevity interventions, including epigenetics and cellular reprogramming
[12:01] The UCLA study that reversed biological age by two years
[15:03] The supplement industry’s crisis of trust, why 75% of studies fail replication, and the critical need for credible voices
[23:18] Mike Levin’s revolutionary bioelectric limb regeneration
[33:57] What the ultimate longevity factor is, and today’s epidemic of loneliness
[39:59] The two pathways to ketosis and why cells prefer ketones over sugar
[44:54] Ketones as a potential alcohol replacement for social occasions
[49:20] Ketones for brain health across all ages and spermidine’s dramatic autophagy effects
[01:05:40] Greg’s most influential teachers, his mother’s profound impact, and my epiphanies I experienced
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Resources Mentioned:
Dr. Michael Levin | https://drmichaellevin.org
CRISPR Gene Editing | https://bit.ly/CRISPPR-GE
Fahy et al, Reversal of epigenetic aging and immunosenescent trends… | https://bit.ly/roepgim
Juvenescence | https://juvlabs.com
RAAD Festival | https://www.raadfest.com
Stephens et al, A randomized, open-label, observational study of the novel ketone ester, bis octanoyl (R)-1,3-butanediol.. | https://bit.ly/4rNymqM
Read: The Body Electric by Robert O. Becker | https://amzn.to/3OgbVf3
Induced Pluripotent Stem Cell | https://bit.ly/ind-plu-stcell
Dr. James Kirkland | https://www.afar.org/james-l.-kirkland
Dr. Walter Bortz | https://www.waltermbortz.com
Read: A Horse Named Lonesome by Luke Storey | https://www.lukestorey.com/lonesome
The Buck Institute | https://www.buckinstitute.org
Roberts et al, A ketogenic diet extends longevity and healthspan in adult mice | https://bit.ly/ktgdiet
Ottaviani et al, Impact of polyphenol oxidase on the bioavailability of flavan-3-ols… | https://rsc.li/46ASMuD
Northwest Wild Foods | https://nwwildfoods.com
Sprevive | https://bit.ly/ch-sprevive
Urolithin A | https://bit.ly/urolithin-A
Timeline Mitopure | https://bit.ly/tl-mitopure
Primeadine Spermidine | https://bit.ly/pr-spmd
Dr. Stephen Simpson | https://bit.ly/stephen-simpson
Charles Perkins Center | https://bit.ly/charlesperkins
Find more from Dr. Greg Bailey:
Dr. Greg Bailey | https://www.drgregbailey.com
Qitone
Website | https://qitone.com/
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https://www.instagram.com/qitone
Find more from Luke:
Luke Storey | https://www.instagram.com/lukestorey/
Facebook | https://www.facebook.com/lukecstorey/
X | https://x.com/MrLukeStorey
YouTube | https://www.youtube.com/lukestorey
LinkedIn | https://www.linkedin.com/in/mrlukestorey
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