Dr. Jared Rutter, PhD, Professor of Biochemistry at the University of Utah and Howard Hughes Medical Institute Investigator, is a leading expert on mitochondria and metabolism. He explains how mitochondria produce the energy for your cells to work but also how they regulate cell growth and replication and thereby contribute to health and disease. We also discuss how mitochondria are linked to aging, cancer, and other diseases. Our conversation explores your metabolism as the composite of trillions of individual cells and points to new ways to improve health, avoid, and treat diseases.
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Jared Rutter
Academic profile: https://medicine.utah.edu/faculty/jared-p-rutter
HHMI: https://www.hhmi.org/scientists/jared-rutter
Lab website: https://rutter.biochem.utah.edu
Publications: https://rutter.biochem.utah.edu/publications
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Timestamps
00:00:00 Jared Rutter
00:02:29 Metabolism, Cells; Aging
00:08:36 Mitochondria, Origin & Cell Complexity
00:13:07 Sponsors: Joovv & BetterHelp
00:15:16 Mitochondria Genome, Inheritance
00:18:18 Mitochondria & Spatial Distribution; Cell-Specific Metabolism
00:25:59 Nutrient Energy, Hormones, Fat Cells
00:31:13 Glucose, ATP Conversion, Pyruvate
00:36:41 Cell Choice: Energy or Growth, Cancer; Virus
00:46:02 Sponsors: AG1 & Eight Sleep
00:48:36 Microbiome, Role of Humans
00:51:44 Molecule Discovery Process, MPC1, MPC2
00:59:42 Cell Resource Sensing, Fasting, Glucagon, Fat Cells; Neurons, Heart
01:07:03 Cell Resource Allocation, MPC, Heart Failure; Disease
01:11:46 Sponsor: Function
01:13:24 Cell Size vs Fuel Balance, Cell Identity & Disease
01:20:43 MPC Discovery, Genetics, Model Systems
01:24:29 Lactate, Oxygen, Exercise; Energy Prioritization Hierarchy
01:31:32 Cancer, Mutations, Metabolism Changes & Warburg Effect
01:36:18 Cancer Challenges & Therapies
01:43:00 Therapy Combinations, Unique Cancer Mutations & Metabolism
01:48:31 Technology to Visualize Metabolism; Disease, Metabolism & Scents
01:56:34 Excess Energy & Mitochondria, Reactive Oxygen Species
02:01:12 Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter
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