**Visit https://www.gatlan.com/ and use cod ‘DAVE’ to unlock a free consultation!**
At 53, Josh Duhamel says he feels better than he did in his 30s.
Host Dave Asprey sits down with actor and Gatlan Health founder Josh Duhamel to talk testosterone, peptides, nootropics, brain health, fatherhood, and what it takes to stay strong as you age.
Josh shares why he started TRT in his early 40s, what changed once he began tracking his hormones, and why he decided to build a health company around hormone optimization. They also discuss injectable testosterone, GLP-1s, peptide quality, hair loss treatments, stem cells, and the importance of medical guidance when experimenting with longevity tools.
The conversation also gets into cognitive performance, including Josh’s past struggles with forgetting lines, his interest in nootropics, and Dave’s experience with Modafinil and Aniracetam. Josh explains why having a newborn and a toddler at 53 has made longevity more personal, while Dave and Josh explore the connection between physical health, spirituality, breathwork, psychedelics, and mental performance.
This is essential listening for anyone interested in testosterone, TRT, peptides, nootropics, brain health, GLP-1s, healthy aging, fatherhood, hormone optimization, and longevity.
You’ll Learn:
-Why Josh started testosterone therapy in his early 40s
-How TRT changed his energy, strength, joints, and motivation
-Why testosterone levels should be individualized
-How injectable, oral, and topical testosterone differ
-Why peptide sourcing matters
-How GLP-1s can affect muscle and body composition
-What Josh has tried for hair loss
-Why brain performance became a major concern for him
-Which nootropics come up for memory, focus, and mental stamina
-Why becoming a father later in life changed how Josh thinks about longevity
-How breathwork, psychedelics, and spirituality fit into the conversation
Resources:
• Visit https://www.gatlan.com/ and use cod ‘DAVE’ to unlock a free consultation
• Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/
• Dave Asprey’s Latest News | Go to https://daveasprey.com/ to join Inside Track today.
• Danger Coffee: https://dangercoffee.com/discount/davetube
• My Daily Supplements: SuppGrade Labs (15% Off)
• Favorite Blue Light Blocking Glasses: TrueDark (15% Off)
Thank you to our sponsors!
– Omni-Biotic | Discover your formula at OmnibioticLife.com. Take 20% off your first order with code ASPREY.
– MOD | Visit mod.com for a consultation and get 10% off your first order plus free shipping with promo code DAVE.
– Timeline | Visit timeline.com/dave and get up to 20% off when you subscribe and save.
– Kenetik | Instead of pushing your system harder, Kenetik feeds your brain the ketones it craves to fuel calm clarity and steady focus. Go to drinkkenetik.com/DAVE and use code DAVE for a discount.
Timestamps:
00:00 – Trailer
01:15 – Intro
07:16 – Alcohol & Hangover Hacks
13:24 – Spirituality & Health
19:36 – Hormone Therapy for Women
24:45 – Inside Gatlan’s Model
30:35 – Potty Training Secrets
38:39 – North Dakota & Fargo
43:57 – Hollywood’s Beauty Secrets
50:19 – Acting Career & Longevity
Connect with Dave Asprey!
Website: https://daveasprey.com
TikTok: https://www.tiktok.com/@daveaspreyofficial
Instagram: https://www.instagram.com/dave.asprey/
Facebook: https://www.facebook.com/Daveaspreyofficial/
X: https://x.com/daveasprey
YouTube: https://www.youtube.com/c/daveaspreybpr
The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/
