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    Home » Essentials: Understanding & Treating Addiction | Dr. Anna Lembke

    Essentials: Understanding & Treating Addiction | Dr. Anna Lembke

    Mal AntoniBy Mal AntoniJune 26, 2025 All Videos 2 Mins Read
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    In this Huberman Lab Essentials episode, my guest is Dr. Anna Lembke, MD, Chief of the Stanford Addiction Medicine Dual Diagnosis Clinic at Stanford University School of Medicine.

    We discuss how dopamine drives reward, motivation and addictive behaviors. Dr. Lembke explains the concept of the pleasure-pain balance of dopamine and how this cycle plays a key role in the development and persistence of addiction. We also discuss some of the challenges of addiction recovery, including withdrawal, relapses and the potential benefits of psychedelic-assisted therapy.

    Episode show notes: https://go.hubermanlab.com/xbtub2m

    Huberman Lab Essentials are short episodes focused on essential science and protocol takeaways from past full-length Huberman Lab episodes. Watch the full-length episode: https://youtu.be/p3JLaF_4Tz8

    Watch more Huberman Lab Essentials episodes: https://youtube.com/playlist?list=PLPNW_gerXa4OGNy1yE-W9IX-tPu-tJa7S

    *Follow Huberman Lab*
    Instagram: https://www.instagram.com/hubermanlab
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    LinkedIn: https://www.linkedin.com/in/andrew-huberman
    Website: https://www.hubermanlab.com
    Newsletter: https://www.hubermanlab.com/newsletter

    *Dr. Anna Lembke*
    Website: https://www.annalembke.com

    *Timestamps*
    00:00:00 Anna Lembke
    00:00:15 Dopamine, Reward & Movement
    00:01:54 Baseline Dopamine; Genetics, Temperament & Addiction
    00:05:24 Addiction, Modern Life & Boredom
    00:07:18 Pleasure-Pain Balance, Dopamine, Addiction
    00:12:39 Resetting Dopamine, Substance or Behavior Recovery, Tool: 30-Day Abstinence
    00:14:26 Relapse, Addiction, Reflexive Behavior, Empathy
    00:18:39 Triggers, Relapse, Dopamine
    00:21:37 Shame, Truth Telling & Recovery
    00:23:58 Addiction, Psychedelic-Assisted Therapy, Psilocybin, MDMA
    00:29:01 Social Media & Addiction, Tool: Intentionality

    Disclaimer & Disclosures: https://www.hubermanlab.com/disclaimer

    Mal Antoni

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