What if you could cheat aging, indulge in life’s guilty pleasures, and still thrive?
Dr. Sandra Kaufmann, the longevity powerhouse behind the Kaufmann Protocol: Why We Age and How to Stop It, joins Dave on The Human Upgrade to share her science-backed blueprint for aging gracefully and optimizing your biology. All you supplementation questions are answered here! With her Seven Tenets of Aging, Dr. Kaufmann reveals the anti-aging secrets that combine natural remedies, nutritional supplements, and wellness strategies to help you live longer, smarter, and stronger—all while enjoying life.
Whether it’s indulging in Diet Coke, hacking your mitochondrial health, managing glycation, or fine-tuning your skincare routines, this episode is packed with anti-aging strategies, beauty tips, and actionable tools to help you embrace healthy aging.
What You’ll Learn:
• The Seven Tenets of Aging and how they support longevity science
• How to combat glycation and other aging culprits with health supplements
• Why “bad” habits don’t have to sabotage your anti-aging secrets
• Insights into vitamins, skincare, and natural remedies for aging well
• How to create a sustainable plan for healthy aging that fits your lifestyle
SPONSORS:
Leela Quantum Tech | Head to https://leelaq.com/DAVE for 10% off.
Timeline | Head to https://www.timeline.com/dave to get 10% off your first order.
Resources:
Supplement Protocol One-Sheet for this episode: https://www.instagram.com/dave.asprey/?hl=en
2025 Biohacking Conference: https://biohackingconference.com/2025
Kaufmann Protocol Website: https://kaufmannprotocol.com
Sandra Kaufmann’s Book – Why We Age and How to Stop It: https://www.amazon.com/Kaufmann-Protocol-Why-Age-Stop/dp/0692089047
Sandra Kaufmann’s Instagram: https://www.instagram.com/kaufmannantiaging/?hl=en
Danger Coffee: https://dangercoffee.com
Dave Asprey’s Website: https://daveasprey.com
Dave Asprey’s Book – Smarter Not Harder: https://daveasprey.com/books
Dave Asprey’s Linktree: https://linktr.ee/daveasprey
Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com
Own an Upgrade Labs: https://ownanupgradelabs.com
Upgrade Labs: https://upgradelabs.com
40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com
Chapters:
00:00 Trailer
00:45 Guest Introduction
02:30 Longevity Insights
04:22 Personal Stories
08:00 Pharmaceuticals
12:26 Diet and Lifestyle
18:19 Seven Tenets
22:04 Sleep and Circadian Rhythms
26:41 NAD and Supplements
37:46 Blood Sugar and AGEs
47:09 Microcirculation
49:08 NRS and Imports
49:18 Cellbex Medication
50:03 Cellbex Benefits
50:41 Alzheimer’s and Cellbex
51:28 Antioxidants
54:26 Stem Cells and Exosomes
58:03 Laser Skin Treatments
01:07:34 Hormones and Longevity
01:20:03 Lithium for Mood
01:27:45 Gender and Longevity
01:32:39 Final Thoughts
Connect with Dave Asprey!
Website: https://daveasprey.com
TikTok: https://www.tiktok.com/@daveaspreyofficial
Instagram: https://www.instagram.com/dave.asprey/
Facebook: https://www.facebook.com/Daveaspreyofficial/
X: https://x.com/daveasprey
YouTube: https://www.youtube.com/c/daveaspreybpr
The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ and https://m.facebook.com/Thehumanupgrade/
