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    Home » Healing From Grief & Loss | Dr. Mary-Frances O’Connor

    Healing From Grief & Loss | Dr. Mary-Frances O’Connor

    Mal AntoniBy Mal AntoniJune 2, 2025 All Videos 3 Mins Read
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    My guest is ⁠Dr. Mary-Frances O’Connor, PhD⁠, Professor of Clinical Psychology and Psychiatry at the University of Arizona and a world expert on the science of grief and loss. We discuss what happens in the brain and body when we grieve, the role of dopamine and yearning in the grieving process, the health risks of getting stuck at particular stages of grief and how to move through loss while also deeply honoring the person, animal or thing that is no longer with us. Dr. O’Connor explains that grief involves cycling back and forth between protest and despair (often guilt and anger too) and explains science-supported ways to move through that process in the healthiest possible way. Everyone experiences grief and loss at some point. Dr. O’Connor provides valuable knowledge and tools to help you navigate grief under any circumstance.

    Episode show notes: https://go.hubermanlab.com/W8yuZuR

    *Thank you to our sponsors*
    AG1: ⁠https://drinkag1.com/huberman⁠
    Wealthfront**: ⁠https://wealthfront.com/huberman⁠
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    **This experience may not be representative of the experience of other clients of Wealthfront, and there is no guarantee that all clients will have similar experiences. Cash Account is offered by Wealthfront Brokerage LLC, Member FINRA/SIPC. The Annual Percentage Yield (“APY”) on cash deposits as of December 27,‬ 2024, is representative, subject to change, and requires no minimum. Funds in the Cash Account are swept to partner banks where they earn the variable‭ APY. Promo terms and FDIC coverage conditions apply. Same-day withdrawal or instant payment transfers may be limited by destination institutions, daily transaction caps, and by participating entities such as Wells Fargo, the RTP® Network, and FedNow® Service. New Cash Account deposits are subject to a 2-4 day holding period before becoming available for transfer.

    *Follow Huberman Lab*
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    *Dr. Mary-Frances O’Connor*
    Website: https://maryfrancesoconnor.org
    University of Arizona academic profile: https://psychology.arizona.edu/person/mary-frances-oconnor
    Grief, Loss and Social Stress (GLASS) Lab: https://maryfrancesoconnor.org/lab
    Neurobiology of Grief International Network: https://www.neurobiologyofgrief.org
    The Grieving Brain: https://amzn.to/4dEUBJ8
    The Grieving Body: https://amzn.to/4kPPTuG
    X: https://twitter.com/doctormfo
    LinkedIn: https://www.linkedin.com/in/maryfrancesoconnor
    Instagram: https://www.instagram.com/doctormfoconnor
    Facebook: https://www.facebook.com/maryfranceso
    Mastodon: https://mastodon.social/@doctormfo@newsie.social

    *Timestamps*
    00:00:00 Mary-Frances O’Connor
    00:02:22 Grief vs Grieving; Love & Bonding, Gone Yet Everlasting
    00:07:42 Sponsors: Wealthfront & BetterHelp
    00:10:29 Sudden vs Slow Death, Attachment, Reframing Relationship
    00:14:52 Religion, Integrating the New Relationship
    00:20:46 Yearning, Dopamine, Brain, Addiction
    00:27:58 Culture & Grief Literacy; Protest, Despair & Hope, New Relationships
    00:40:09 Sponsors: AG1 & Helix Sleep
    00:43:21 Protest, Despair & Transmutation; Changing Attachment Hierarchy
    00:52:04 Bereavement Support, Medical Risk
    01:05:27 Culture, Alcohol & Death; Dying of a Broken Heart, Medical Risk
    01:13:40 Sponsor: Function
    01:15:28 Navigating Grief, Emotions & Body, Tool: Progressive Muscle Relaxation
    01:23:57 Grief Stages; Permission & Coping, Judgment & Guilt; Lessons from Grief
    01:35:44 Grieving Suicide, Rumination, Tool: Shifting Environment
    01:47:24 Belief Systems, Religion & Grief
    01:54:17 Afterlife, Contemplating Death
    01:58:35 Tools: Contemplating Death; Life Celebration, Terror Management, Empathy
    02:07:46 Mental Oscillation, Dual Model of Bereavement
    02:14:00 Avoidance; Remembering a Loved One, Resilience; Getting Worse & Seeking Professional Help
    02:22:15 Time Perception & End of Life, Motivation & Energy
    02:30:01 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter

    Disclaimer & Disclosures: https://www.hubermanlab.com/disclaimer

    Mal Antoni

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