Explore Calroy’s vascular health and joint support supplements, including Arterosil, Vascanox, and Cartigenix, at https://calroy.com/dave
Cartilage Regeneration, Joint Pain, Nitric Oxide, Blood Flow, Muscle Strength & Longevity with Kiran Krishnan
Host Dave Asprey sits down with Kiran Krishnan, research microbiologist, systems biology researcher, and co-founder of Microbiome Labs, to explore cartilage regeneration, joint pain, osteoarthritis, nitric oxide, vascular health, inflammation, muscle growth, gut health, bone density, and the biological mechanisms that influence how the body ages.
Kiran Krishnan is a research microbiologist, health and wellness expert, and entrepreneur who specializes in the human microbiome, gut health, inflammation, and systems biology. Over the past 20 years, he has founded several successful health and supplement companies, including co-founding and leading Microbiome Labs, a leading microbiome therapeutics brand among healthcare professionals. He is also a co-founder and partner in three other health companies. Kiran has conducted and published scientific research, contributed chapters to scientific textbooks, holds global patents, and is a sought-after speaker on human health and the microbiome.
His latest work explores the relationship between blood vessel health, chronic inflammation, and the body’s ability to repair damaged cartilage. Through research involving compounds designed to support vascular function, nitric oxide production, and joint health, Kiran is investigating whether age-related tissue degeneration can be slowed or potentially reversed.
This episode is essential listening for anyone interested in cartilage regeneration, osteoarthritis, chronic joint pain, nitric oxide, blood circulation, vascular health, inflammation, muscle growth, strength training, gut health, bone density, menopause, cellular repair, supplements, biohacking, and the science of maintaining physical performance as you age.
You’ll Learn:
-Why cartilage breaks down with age and how impaired blood flow and chronic inflammation interfere with joint repair
-What Kiran’s clinical research suggests about cartilage regeneration and joint recovery in people with osteoarthritis
-How nitric oxide and the endothelial glycocalyx influence circulation, cardiovascular health, cognitive function, and longevity
-Why functional strength may be more important than muscle size for healthy aging, and how blood flow affects muscle growth and recovery
-How walking after meals, supporting digestion, and improving vascular function may benefit blood sugar regulation and gut health
-What emerging research suggests about bone regeneration, postbiotics, and maintaining bone density during menopause and aging
Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind.
Resources:
• Grab A Discount On Calroy’s Vascular Health And Joint Support Supplements, Including Arterosil, Vascanox, and Cartigenix, at https://calroy.com/dave
• Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/
• Dave Asprey’s Latest News | Go to https://daveasprey.com/ to join Inside Track today.
• Danger Coffee: https://dangercoffee.com/discount/davetube
• My Daily Supplements: SuppGrade Labs (15% Off)
• Favorite Blue Light Blocking Glasses: TrueDark (15% Off)
Thank you to our sponsors!
– ALP | Go to alppouch.com, code DAVE for 10% off.
– Visit www.myvitalc.com/davesfav to unlock Dave’s discount
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– Omni-Biotic | Discover your formula at OmnibioticLife.com. Take 20% off your first order with code ASPREY.
Timestamps:
00:00 — Trailer
01:05 — Intro
04:44 — The Glycocalyx Explained
10:30 — Why Joints Degrade
15:16 — Rebuilding Cartilage
21:17 — Nitric Oxide & Gut Health
26:28 — Hacking the Cephalic Response
31:23 — Strength vs. Size for Longevity
37:47 — Muscle Building Supply System
42:51 — New Bone Regeneration Product
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