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    Home » Essentials: Build a Healthy Gut Microbiome | Dr. Justin Sonnenburg

    Essentials: Build a Healthy Gut Microbiome | Dr. Justin Sonnenburg

    Mal AntoniBy Mal AntoniDecember 11, 2025 All Videos 2 Mins Read
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    In this ⁠Huberman Lab Essentials⁠ episode, my guest is Dr. Justin Sonnenburg, PhD, a professor of microbiology and immunology at Stanford University.

    We discuss how microbes in our gut impact our mental and physical health and how diet and the environment affect the gut microbiome. We explain how lifestyle factors such as antibiotics and Western-style diets (high fat, low fiber and rich in processed foods) can damage gut diversity and whether prebiotics or probiotics are useful tools. Throughout the episode, we highlight evidence-based dietary and lifestyle strategies for improving gut health.

    Show notes: https://go.hubermanlab.com/XsesnGn

    Huberman Lab Essentials are short episodes focused on essential science and protocol takeaways from past full-length Huberman Lab episodes. Watch the full-length episode: https://youtu.be/ouCWNRvPk20

    Watch more Huberman Lab Essentials: https://youtube.com/playlist?list=PLPNW_gerXa4OGNy1yE-W9IX-tPu-tJa7S

    *Timestamps*
    00:00:00 Justin Sonnenburg
    00:00:20 What is the Microbiome?
    00:02:55 Microbiome Origin, Babies, Environmental Factors
    00:04:47 Healthy Microbiome, Individuality; Industrialized vs Traditional Populations
    00:07:06 “Reprogramming” the Gut Microbiome; Antibiotics, Western Diet
    00:11:34 Cleanses & Fasting
    00:12:31 Processed Foods & Microbiome, Artificial Sweeteners, Emulsifiers
    00:16:11 Inflammatory Western Diseases, Microbiome & Immune System
    00:19:07 Fiber, Fermented Foods & Microbiome, Tool: Fermented Food Consumption
    00:25:36 Fiber, Depleted Microbiome, Industrialization, Sanitation
    00:27:09 Antibiotics, Over-Sanitation, Disease, Hand Washing
    00:29:02 Probiotics, Tool: Product Validation,
    00:30:51 Prebiotics, Tool: Plant Consumption
    00:33:24 Good Gut Book, Justin’s Research

    #HubermanLab #Science #GutHealth #GutMicrobiome

    Disclaimer & Disclosures: https://www.hubermanlab.com/disclaimer

    Mal Antoni

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