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    Home » How Depression Awakens the Soul (and the Science That Proves It) | Dr. Lisa Miller

    How Depression Awakens the Soul (and the Science That Proves It) | Dr. Lisa Miller

    Mal AntoniBy Mal AntoniOctober 28, 2025 All Videos 2 Mins Read
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    Clinical psychologist and bestselling author Dr. Lisa Miller joins us to reveal the groundbreaking neuroscience that connects spirituality with mental health, purpose, and human flourishing. Drawing from decades of research at Columbia University, she shares how spiritual awareness literally changes the brain — rewiring us for resilience, compassion, and meaning. From the awakened brain to the power of awe, Lisa bridges empirical science with lived spirituality, showing how we are biologically built for connection with something greater than ourselves.

    www.bioptimizers.com/knowthyself
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    Andrés Book Recs: https://www.knowthyselfpodcast.com/book-list

    ___________
    00:00 Intro
    03:40 What Is the Awakened Brain?
    07:10 How Spirituality Changes the Brain
    10:50 Depression as a Doorway to Awakening
    14:25 The Biology of Faith and Meaning
    18:05 The Parietal Lobe and the Sense of Oneness
    22:00 From Egoic Mind to Spiritual Awareness
    26:15 Dorsal vs. Ventral Attention Networks Explained
    30:10 How Prayer and Meditation Rewire the Brain
    34:00 The Neuroscience of Love and Connection
    38:25 What Happens in the Brain During Awe
    42:10 Synchronicity and the Science of Guidance
    46:00 Raising Spiritually Connected Children
    50:20 Addiction, Recovery, and the Search for Spirit
    54:35 The Brain as an Antenna for Consciousness
    59:15 Science Meets Mysticism: Where They Overlap
    1:03:30 The Future of Mental Health and Spirituality
    1:07:40 Reawakening the Innate Spiritual Brain
    1:12:00 Living with Awe, Service, and Gratitude
    1:16:10 Closing Reflections
    ___________

    Episode Resources:
    https://www.lisamillerphd.com/
    https://www.instagram.com/dr.lisamiller/

    https://www.instagram.com/andreduqum/
    https://www.instagram.com/knowthyself/
    https://www.youtube.com/@knowthyselfpodcast
    https://www.knowthyselfpodcast.com

    Listen to the show:
    Spotify: https://spoti.fi/4bZMq9l
    Apple: https://apple.co/4iATICX

    Mal Antoni

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