Dr. Steven Gundry breaks down everything you need to know about NAD, NMN, and NR: what they are, why they matter, and why the vast majority of NAD supplements on the market are failing the people taking them. Independent lab studies have found that most NMN products contain less than 1% of their claimed dose by the time they reach your cells — and even the ones that do work are only solving half the problem.
We are excited to announce the launch of Gundry MD Elevate NAD+. Formulated with stabilized NMN (nicotinamide mononucleotide) delivered via a novel patent-pending beadlet system, Elevate NAD+ is designed to meaningfully raise the body’s NAD+ levels.
Order Now! – https://rebrand.ly/elevatenadplus-pr
Use code PODCAST25 for 25% off at checkout. My Account and subscription price excluded. Can not be combined with other offers. Does not apply to bundles, devices and digital products.
If you’ve been struggling with low energy, brain fog, slow recovery, or the kind of exhaustion that a full night’s sleep can’t fix, the answer might come down to a single molecule — NAD — and the fact that your levels have been quietly declining for years without anyone telling you.
Dr. Gundry explains the three hidden reasons your NAD keeps depleting as you age — including an enzyme called CD38 that becomes increasingly aggressive over time, senescent "zombie cells" that drain your NAD stores without giving anything back, and oxidative stress that burns through your reserves daily. He also shares why his 25-year friendship with Harvard’s Dr. David Sinclair shaped his thinking on sirtuins, longevity, and mitochondrial health — and why he refused to release his own NAD supplement until he could address all of it at once.
Questions this episode answers:
→ What is NAD and why does it decline so dramatically with age?
→ What is the real difference between NMN and NR — and do you need both?
→ Why are most NAD supplements on the market ineffective?
→ What is CD38, and how is it destroying your NAD levels without you knowing?
→ Can fasting and strength training actually raise NAD naturally?
→ What age should you start supporting your NAD levels?
→ What should you actually look for — and avoid — when buying an NAD supplement?
00:00 – Why NAD Is the One Longevity Molecule That Actually Lives Up to the Hype
00:23 – What NAD Does Inside Your Body — And Why Losing It Is Costing You Everything
01:27 – The Real Reason You’re Exhausted, Foggy & Recovering Slower Than You Used To
06:18 – Why NMN & NR Supplements Are Failing You (And What the Studies Actually Show)
10:17 – The Age That NAD Decline Starts — It’s Much Earlier Than You Think
13:05 – Why Dr. Gundry Refused to Make an NAD Supplement for 25 Years
13:32 – The Leaking Bucket Problem: What Every Other NAD Supplement Gets Wrong
14:05 – Elevate NAD+: The Formula Built to Fix All of It
Order Now! – https://rebrand.ly/elevatenadplus-pr
Use code PODCAST25 for 25% off at checkout. My Account and subscription price excluded. Can not be combined with other offers. Does not apply to bundles, devices and digital products.
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